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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL91938
Molecular formula	C21H18F3NO3
IUPAC name	8-methoxy-3-[[4-(trifluoromethyl)phenyl]methyl]-2,4-dihydro-1H-chromeno[3,4-c]pyridin-5-one
Molecular weight	389.374
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	3.7
Synonyms	SCHEMBL8580935 8-Methoxy-3-(4-trifluoromethyl-benzyl)-1,2,3,4-tetrahydro-chromeno[3,4-c]pyridin-5-one APSWOEYPVXOOHK-UHFFFAOYSA-N BDBM50059501
Inchi Key	APSWOEYPVXOOHK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H18F3NO3/c1-27-15-6-7-17-16-8-9-25(12-18(16)20(26)28-19(17)10-15)11-13-2-4-14(5-3-13)21(22,23)24/h2-7,10H,8-9,11-12H2,1H3
PubChem CID	10318141
ChEMBL	CHEMBL91938
IUPHAR	N/A
BindingDB	50059501
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11335	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
11333	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
11334	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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