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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL280297
Molecular formula	C28H22F3N3O2
IUPAC name	5-methoxy-N-(3-phenyl-5-pyridin-3-ylphenyl)-6-(trifluoromethyl)-2,3-dihydroindole-1-carboxamide
Molecular weight	489.498
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.7
Synonyms	5-Methoxy-1-[5-phenyl-3-(pyrid-3-yl)phenylcarbamoyl]-6-trifluoromethyl Indoline SCHEMBL7041275 AQKLFYUGEBTKMZ-UHFFFAOYSA-N 5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid (5-pyridin-3-yl-biphenyl-3-yl)-amide BDBM50086057 N-[3-(3-Pyridyl)-5-phenylphenyl]-5-methoxy-6-(trifluoromethyl)-2,3-dihydro-1H-indole-1-carboxamide [ Show all ]
Inchi Key	AQKLFYUGEBTKMZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H22F3N3O2/c1-36-26-15-19-9-11-34(25(19)16-24(26)28(29,30)31)27(35)33-23-13-21(18-6-3-2-4-7-18)12-22(14-23)20-8-5-10-32-17-20/h2-8,10,12-17H,9,11H2,1H3,(H,33,35)
PubChem CID	10767350
ChEMBL	CHEMBL280297
IUPHAR	N/A
BindingDB	50086057
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11853	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
11855	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
11854	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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