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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL306903
Molecular formula	C19H26F2N2O2
IUPAC name	(2R)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenyl-N-(piperidin-4-ylmethyl)acetamide
Molecular weight	352.426
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	2.5
Synonyms	(alphaR)-alpha-Hydroxy-alpha-[(1R)-3,3-difluorocyclopentane-1beta-yl]-N-(4-piperidinylmethyl)benzeneacetamide BDBM50129403 (R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-piperidin-4-ylmethyl-acetamide
Inchi Key	ARNGHJQKGZGVCU-APWZRJJASA-N
Inchi ID	InChI=1S/C19H26F2N2O2/c20-18(21)9-6-16(12-18)19(25,15-4-2-1-3-5-15)17(24)23-13-14-7-10-22-11-8-14/h1-5,14,16,22,25H,6-13H2,(H,23,24)/t16-,19+/m1/s1
PubChem CID	44309089
ChEMBL	CHEMBL306903
IUPHAR	N/A
BindingDB	50129403
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12597	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
12599	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
12598	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590

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