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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	QUISQUALIC ACID
Molecular formula	C5H7N3O5
IUPAC name	(2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid
Molecular weight	189.127
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	-3.9
Synonyms	(2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid. SR-01000075471-5 ZINC897456 3-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine AKOS024456826 C08296 D06DUE HMS2233G05 LS-175398 NCGC00024489-05 SCHEMBL13319908 (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID ST50825297 1p1o 8OC22C1B99 BDBM17660 CHEBI:8734 EU-0101039 L(+)-alpha-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid MolPort-003-939-212 PDSP2_000801 Quisqualate (2S)-2-amino-3-(3,5-dioxo(1,2,4-oxadiazolidin-2-yl))propanoic acid SR-01000075471 UNII-8OC22C1B99 2jbk AC1Q6GK0 BN0434 CHEMBL279956 GTPL1370 Lopac0_001039 NCGC00024489-03 Quisqualic acid, powder (L)-(+)-?-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid SR-01000597681 1mm6 [3H]quisqualate 52809-07-1 ASNFTDCKZKHJSW-REOHCLBHSA-N C5H7N3O5 D0W6JO HMS3263O19 MFCD00069337 NCGC00261724-01 ()-Quisqualic Acid SCHEMBL136819 1,2,4-Oxadiazolidine-2-propanoic acid, alpha-amino-3,5-dioxo-, (S)- Tocris-0188 2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-propionic acid(Quisqualic acid) AC1L23YS BDBM50164445 CHEMBL168279 FCH4012693 L-210 NCGC00024489-01 Q 2128 Quisqualate, L (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid SR-01000075471-1 V0329 2or4 ACM52809071 C-52964 CTK4J6551 GTPL1372 LP01039 NCGC00024489-04 QUS (S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid SR-01000597681-1 1mm7 809Q071 BCP13297 CCG-205116 DB02999 KB-60323 MLS001074741 PDSP1_000814 (+)-Quisqualic acid SMR000471890 1,2,4-Oxadiazolidine-2-propanoicacid, a-amino-3,5-dioxo-, (aS)- Tox21_501039 2-amino-3-(3,5-dioxo[1,2,4]oxadiazolidin-2-yl)propionic acid AC1ODZB5 beta-(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)-L-alanine FT-0604435 L-Quisqualic acid NCGC00024489-02 QC-11635 [ Show all ]
Inchi Key	ASNFTDCKZKHJSW-REOHCLBHSA-N
Inchi ID	InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
PubChem CID	40539
ChEMBL	CHEMBL279956
IUPHAR	1370, 1372
BindingDB	17660
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13315	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
13318	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
13313	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
13314	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
13322	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
13326	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
13317	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
13320	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
13316	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
13323	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
13319	Metabotropic glutamate receptor 6	O15303	GRM6	Homo sapiens (Human)	877
13328	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
13321	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
13325	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
13327	Metabotropic glutamate receptor 8	P47743	Grm8	Mus musculus (Mouse)	908
13324	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460

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