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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL185438
Molecular formula	C28H29ClN4O3S
IUPAC name	7-chloro-4-(2-cyclopentylethoxy)-2-oxo-N-(1,2,5-thiadiazol-3-yl)-3-(3,4,5-trimethylphenyl)-1H-quinoline-6-carboxamide
Molecular weight	537.075
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	6.5
Synonyms	BDBM50155358 L020823 7-Chloro-4-(2-cyclopentyl-ethoxy)-2-oxo-3-(3,4,5-trimethyl-phenyl)-1,2-dihydro-quinoline-6-carboxylic acid [1,2,5]thiadiazol-3-ylamide
Inchi Key	ASVLYALZPZGNFP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H29ClN4O3S/c1-15-10-19(11-16(2)17(15)3)25-26(36-9-8-18-6-4-5-7-18)21-12-20(22(29)13-23(21)31-28(25)35)27(34)32-24-14-30-37-33-24/h10-14,18H,4-9H2,1-3H3,(H,31,35)(H,32,33,34)
PubChem CID	10208964
ChEMBL	CHEMBL185438
IUPHAR	N/A
BindingDB	50155358
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13576	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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