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Ligand

NameCHEMBL211265
Molecular formulaC22H23N5O2
IUPAC nameN-[4-[2,4-diamino-6-(phenylmethoxymethyl)pyrimidin-5-yl]phenyl]cyclopropanecarboxamide
Molecular weight389.459
Hydrogen bond acceptor6
Hydrogen bond donor3
XlogP1.9
SynonymsSCHEMBL6259740
BDBM19358
LS-193094
2,4-diaminopyrimidine-based antagonist, 13d
n-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5-yl}phenyl)cyclopropanecarboxamide
Inchi KeyATKRWWYTIGCNEA-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H23N5O2/c23-20-19(15-8-10-17(11-9-15)25-21(28)16-6-7-16)18(26-22(24)27-20)13-29-12-14-4-2-1-3-5-14/h1-5,8-11,16H,6-7,12-13H2,(H,25,28)(H4,23,24,26,27)
PubChem CID11349789
ChEMBLCHEMBL211265
IUPHARN/A
BindingDB19358
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 1
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GLASS IDNameUniProtGeneSpeciesLength
14050Growth hormone secretagogue receptor type 1Q92847GHSRHomo sapiens (Human)366

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