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Ligand

Name180083-23-2
Molecular formulaC32H32N4O3
IUPAC name[4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl]-(1'-methylspiro[6,7-dihydro-2H-furo[2,3-f]indole-3,4'-piperidine]-5-yl)methanone
Molecular weight520.633
Hydrogen bond acceptor6
Hydrogen bond donor0
XlogP5.6
SynonymsCTK8B9472
L000538
NCGC00015918-02
SCHEMBL7746188
[4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]phenyl]-(1'-methylspiro[6,7-dihydro-2H-furo[2,3-f]indole-3,4'-piperidine]-5-yl)methanone
[ Show all ]
Inchi KeyATQMRMGXINTJHV-UHFFFAOYSA-N
Inchi IDInChI=1S/C32H32N4O3/c1-20-16-25(30-33-21(2)39-34-30)8-9-26(20)22-4-6-23(7-5-22)31(37)36-13-10-24-17-29-27(18-28(24)36)32(19-38-29)11-14-35(3)15-12-32/h4-9,16-18H,10-15,19H2,1-3H3
PubChem CID3378093
ChEMBLCHEMBL281350
IUPHAR130
BindingDB50084959
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 28
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
142315-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
142405-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
142265-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
142465-hydroxytryptamine receptor 1BO08892HTR1BCavia porcellus (Guinea pig)389
142475-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
142395-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
142275-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
142485-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
142445-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
142375-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
142325-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
142385-hydroxytryptamine receptor 4Q13639HTR4Homo sapiens (Human)388
142415-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
142515-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
14229Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
14228Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
14233Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
14245Alpha-2B adrenergic receptorP30545Adra2bMus musculus (Mouse)450
14243Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
14235Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413

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