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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1945848
Molecular formula	C25H28N4O2
IUPAC name	5-[4-(1-cyclobutylpiperidin-4-yl)oxyphenyl]-6-methyl-2-pyridin-2-ylpyridazin-3-one
Molecular weight	416.525
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.7
Synonyms	BDBM50363317 SCHEMBL1375779
Inchi Key	AUHYFUJMJOAHEZ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H28N4O2/c1-18-23(17-25(30)29(27-18)24-7-2-3-14-26-24)19-8-10-21(11-9-19)31-22-12-15-28(16-13-22)20-5-4-6-20/h2-3,7-11,14,17,20,22H,4-6,12-13,15-16H2,1H3
PubChem CID	24996645
ChEMBL	CHEMBL1945848
IUPHAR	N/A
BindingDB	50363317
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14650	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
14651	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
14646	Histamine H3 receptor	Q9QYN8	Hrh3	Rattus norvegicus (Rat)	445
14648	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
14647	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390
14649	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466

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