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Ligand

NameCHEMBL1946122
Molecular formulaC22H25ClFNO2
IUPAC name(1S,5R)-3-(4-chlorophenyl)-8-[3-(4-fluorophenoxy)propyl]-8-azabicyclo[3.2.1]octan-3-ol
Molecular weight389.895
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.8
SynonymsBDBM50363903
Inchi KeyAWIYLVWAILOVMX-RLAPIPATSA-N
Inchi IDInChI=1S/C22H25ClFNO2/c23-17-4-2-16(3-5-17)22(26)14-19-8-9-20(15-22)25(19)12-1-13-27-21-10-6-18(24)7-11-21/h2-7,10-11,19-20,26H,1,8-9,12-15H2/t19-,20+,22?
PubChem CID13091358
ChEMBLCHEMBL1946122
IUPHARN/A
BindingDB50363903
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
160735-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
160745-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
16076D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
16075D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
16078D(4) dopamine receptorP30729Drd4Rattus norvegicus (Rat)387
16077Histamine H1 receptorP35367HRH1Homo sapiens (Human)487

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