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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Etamiphylline
Molecular formula	C13H21N5O2
IUPAC name	7-[2-(diethylamino)ethyl]-1,3-dimethylpurine-2,6-dione
Molecular weight	279.344
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	0.3
Synonyms	Etamiphylline [INN-French] Milheparin NSC_28329 1, {3-Dimethyl-7-[2-(diethylamino)ethyl]xanthine} Theophylline, 7-(2-diethylamino)ethyl- 221A91BQ2S {7-[2-(Diethylamino)ethyl]theophylline} 7-(2-Diethylaminoethyl)theophylline 7-[2-(Diethylamino)ethyl]theophylline Camphophyline Diaethylaminoaethyl-theophyllin(GERMAN) Etamifillina F3229-0069 Millophylline R-3588 17140-68-0 (mono-hydrochloride) UNII-221A91BQ2S 59547-58-9 7-[(Diethylamino)ethyl]theophylline AKOS024481061 CHEMBL2104264 Diethylaminoethyltheophylline Etamiphyllin LS-149479 NSC-38348 Soluphyline 1H-Purine-2,6-dione, 7-(2-(diethylamino)ethyl)-3,7-dihydro-1,3-dimethyl- (9CI) {7-[(Diethylamino)ethyl]theophylline} 7-(2-(Diethylamino)ethyl)theophylline 7-[2-(Diethylamino)ethyl]-1,3-dimethylxanthine BRN 0291098 Diaethylaminoaethyl-theophyllin Etamifilina Etamiphyllinum Milliphylline Parephyllin 1,3-Dimethyl-7-(2-(diethylamino)ethyl)xanthine Theophylline, 7-[2-(diethylamino)ethyl]- 314-35-2 7-(beta-Diethylaminoethyl)theophylline CAS_314-35-2 Dietamiphylline Etamifillina [DCIT] FT-0699597 MolPort-006-111-199 SCHEMBL355304 1H-Purine-2, 7-[2-(diethylamino)ethyl]-3,7-dihydro-1,3-dimethyl- VU0606073-1 7-(2-(Diethylamino)ethyl)-1,3-dimethylxanthine 7-[2-(diethylamino)ethyl]-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione AWKLBIOQCIORSB-UHFFFAOYSA-N Corafil Diethylaminoethyltheophylline heparinate Etamiphyllin heparinate Etamiphylline (INN) MCULE-6206874864 NSC38348 Theophylline, 7-(2-(diethylamino)ethyl)- 1H-Purine-2,6-dione, 7-[2-(diethylamino)ethyl]-3,7-dihydro-1,3-dimethyl- {7-[2-(Diethylamino)ethyl]-1,} 3-dimethylxanthine 7-(2-diethylaminoethyl)-1,3-dimethylpurine-2,6-dione 7-[2-(Diethylamino)ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione C13H21N5O2 Diaethylaminoaethyl-theophyllin [German] Etamifilina [INN-Spanish] Etamiphyllinum [INN-Latin] Millophyline Queryl 1,3-Dimethyl-7-[2-(diethylamino)ethyl]xanthine Theophylline, {7-[2-(diethylamino)ethyl]-} 4-26-00-02409 (Beilstein Handbook Reference) 7-(Diethylaminoethyl)theophylline AC1L1F3S CHEBI:135157 Diethylaminoethyl theophylline Etaminophylline Etamiphyllin [INN] Heparin, compd. with 7-(2-(diethylamino)ethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione (1:1) NSC 38348 Solufilina 1H-Purine-2,6-dione, 7-(2-(diethylamino)ethyl)-3,7-dihydro-1,3-dimethyl- ZINC1377 7-(2-(Diethylamino)ethyl)-Theophylline 7-[2-(Diethylamino)ethyl]-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione # BDBM82014 D07378 EINECS 206-244-6 [ Show all ]
Inchi Key	AWKLBIOQCIORSB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C13H21N5O2/c1-5-17(6-2)7-8-18-9-14-11-10(18)12(19)16(4)13(20)15(11)3/h9H,5-8H2,1-4H3
PubChem CID	28329
ChEMBL	N/A
IUPHAR	N/A
BindingDB	82014
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16122	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
555545	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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