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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-V85UF0B9WX
Molecular formula	C25H25N5O
IUPAC name	2-ethyl-4-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methoxy]-5,6,7,8-tetrahydroquinoline
Molecular weight	411.509
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.2
Synonyms	V85UF0B9WX 2-Ethyl-4-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-5,6,7,8-tetrahydro-quinoline ICI-D6888 free base SCHEMBL686005 138620-04-9 CHEMBL418226 ZD-6888 2-Ethyl-4-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethoxy]-5,6,7,8-tetrahydro-quinoline L005949 BDBM50047126 2-Ethyl-4-(2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethoxy)-5,6,7,8-tetrahydroquinoline ICI-D-6888 free base 2-Ethyl-4-[[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]oxy]-5,6,7,8-tetrahydroquinoline Quinoline, 2-ethyl-5,6,7,8-tetrahydro-4-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methoxy)- [ Show all ]
Inchi Key	AWZMTWHHQXOWQR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H25N5O/c1-2-19-15-24(22-9-5-6-10-23(22)26-19)31-16-17-11-13-18(14-12-17)20-7-3-4-8-21(20)25-27-29-30-28-25/h3-4,7-8,11-15H,2,5-6,9-10,16H2,1H3,(H,27,28,29,30)
PubChem CID	9887844
ChEMBL	CHEMBL418226
IUPHAR	N/A
BindingDB	50047126
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16477	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
16478	Type-1 angiotensin II receptor	Q9WV26	AGTR1	Cavia porcellus (Guinea pig)	359

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