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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL471340
Molecular formula	C27H36Cl2N4O3
IUPAC name	N-[(2R)-3-(2,4-dichlorophenyl)-1-[4-[2-(1-hydroxy-3-methylbutyl)phenyl]piperazin-1-yl]-1-oxopropan-2-yl]-2-(methylamino)acetamide
Molecular weight	535.51
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	4.3
Synonyms	BDBM50245486 N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3-methylbutyl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)-2-(methylamino)acetamide
Inchi Key	AXBQVTBYSIEJPU-XQZUBTRRSA-N
Inchi ID	InChI=1S/C27H36Cl2N4O3/c1-18(2)14-25(34)21-6-4-5-7-24(21)32-10-12-33(13-11-32)27(36)23(31-26(35)17-30-3)15-19-8-9-20(28)16-22(19)29/h4-9,16,18,23,25,30,34H,10-15,17H2,1-3H3,(H,31,35)/t23-,25?/m1/s1
PubChem CID	44562440
ChEMBL	CHEMBL471340
IUPHAR	N/A
BindingDB	50245486
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16536	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
16535	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
16537	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325

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