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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL562781
Molecular formula	C23H25N3O4
IUPAC name	3-[[3,4-dioxo-2-[[(1R)-1-phenylpropyl]amino]cyclobuten-1-yl]amino]-2-hydroxy-N,N,4-trimethylbenzamide
Molecular weight	407.47
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	4.0
Synonyms	BDBM50297740 SCHEMBL12086661 (R)-3-(3,4-dioxo-2-(1-phenylpropylamino)cyclobut-1-enylamino)-2-hydroxy-N,N,4-trimethylbenzamide
Inchi Key	AXLRSENOHOPWNY-MRXNPFEDSA-N
Inchi ID	InChI=1S/C23H25N3O4/c1-5-16(14-9-7-6-8-10-14)24-18-19(22(29)21(18)28)25-17-13(2)11-12-15(20(17)27)23(30)26(3)4/h6-12,16,24-25,27H,5H2,1-4H3/t16-/m1/s1
PubChem CID	44249825
ChEMBL	CHEMBL562781
IUPHAR	N/A
BindingDB	50297740
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
16837	C-X-C chemokine receptor type 1	P25024	CXCR1	Homo sapiens (Human)	350
16836	C-X-C chemokine receptor type 2	P25025	CXCR2	Homo sapiens (Human)	360

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