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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-(4-chlorophenyl)-N-(2-methoxy-5-nitrophenyl)-1-oxo-1,2-dihydroisoquinoline-4-carboxamide
Molecular formula	C23H16ClN3O5
IUPAC name	2-(4-chlorophenyl)-N-(2-methoxy-5-nitrophenyl)-1-oxoisoquinoline-4-carboxamide
Molecular weight	449.847
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.1
Synonyms	2-(4-chlorophenyl)-N-(2-methoxy-5-nitrophenyl)-1-oxoisoquinoline-4-carboxamide MolPort-007-952-399 SR-01000147288 MCULE-6772135679 AC1ND3J2 Oprea1_839453 CHEMBL1466399 SR-01000147288-1 MLS000584898 AKOS002130623 SMR000207283 HMS2547G24 ZINC2937992 [ Show all ]
Inchi Key	AXYJVOCPPVHMDU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H16ClN3O5/c1-32-21-11-10-16(27(30)31)12-20(21)25-22(28)19-13-26(15-8-6-14(24)7-9-15)23(29)18-5-3-2-4-17(18)19/h2-13H,1H3,(H,25,28)
PubChem CID	4569017
ChEMBL	CHEMBL1466399
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17220	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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