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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000039260
Molecular formula	C14H14N4O3
IUPAC name	4-(methoxymethyl)-2-[(6-methyl-1,3-benzoxazol-2-yl)amino]-1H-pyrimidin-6-one
Molecular weight	286.291
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	0.9
Synonyms	AC1LD0RC MCULE-4669291953 NCGC00021073-02 6-(methoxymethyl)-2-[(6-methyl-1,3-benzoxazol-2-yl)amino]-1H-pyrimidin-4-one DNDI1417132 SMR000040429 AKOS005715777 CHEMBL1492017 Oprea1_213976 6-(methoxymethyl)-2-[(6-methyl-1,3-benzoxazol-2-yl)amino]pyrimidin-4-ol HMS2177P12 STL163811 BDBM43348 NCGC00021073-01 cid_659383 Oprea1_438899 [ Show all ]
Inchi Key	AYNYOFBZPWQVCY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H14N4O3/c1-8-3-4-10-11(5-8)21-14(16-10)18-13-15-9(7-20-2)6-12(19)17-13/h3-6H,7H2,1-2H3,(H2,15,16,17,18,19)
PubChem CID	135449568
ChEMBL	CHEMBL1492017
IUPHAR	N/A
BindingDB	43348
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17617	Apelin receptor	P35414	APLNR	Homo sapiens (Human)	380
17615	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
17616	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
17618	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
17620	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
465037	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
17619	Type-1 angiotensin II receptor	P30556	AGTR1	Homo sapiens (Human)	359

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