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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL474502
Molecular formula	C20H18Cl2N2O4S2
IUPAC name	2-[10-(3,4-dichlorophenyl)sulfanyl-1-methylsulfonyl-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl]acetic acid
Molecular weight	485.394
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.8
Synonyms	BDBM50277444 SCHEMBL992456 2-(10-(3,4-dichlorophenylthio)-1-(methylsulfonyl)-6,7,8,9-tetrahydropyrido[3,4-b]indolizin-9-yl)acetic acid
Inchi Key	AZEWLQWEZLEILO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18Cl2N2O4S2/c1-30(27,28)20-17-15(6-7-23-20)24-8-2-3-11(9-16(25)26)18(24)19(17)29-12-4-5-13(21)14(22)10-12/h4-7,10-11H,2-3,8-9H2,1H3,(H,25,26)
PubChem CID	10028338
ChEMBL	CHEMBL474502
IUPHAR	N/A
BindingDB	50277444
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18083	Prostaglandin D2 receptor	Q13258	PTGDR	Homo sapiens (Human)	359
18084	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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