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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1LRXHJ
Molecular formula	C24H29F3N2O3
IUPAC name	5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-3-methyl-N-[3-(trifluoromethyl)phenyl]furan-2-carboxamide
Molecular weight	450.502
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.9
Synonyms	ASN 06744256 HMS2485F06 5-tert-butyl-N-[2-(cyclopentylamino)-2-oxoethyl]-3-methyl-N-[3-(trifluoromethyl)phenyl]furan-2-carboxamide MLS000557039 CHEMBL1578905 5-tert-Butyl-3-methyl-furan-2-carboxylic acid cyclopentylcarbamoylmethyl-(3-trifluoromethyl-phenyl)-amide SMR000173545 [ Show all ]
Inchi Key	AZYMDZVQBIJHJG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H29F3N2O3/c1-15-12-19(23(2,3)4)32-21(15)22(31)29(14-20(30)28-17-9-5-6-10-17)18-11-7-8-16(13-18)24(25,26)27/h7-8,11-13,17H,5-6,9-10,14H2,1-4H3,(H,28,30)
PubChem CID	1454984
ChEMBL	CHEMBL1578905
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18610	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
18611	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
18609	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
465153	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
18608	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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