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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1771084
Molecular formula	C21H28N4O2S
IUPAC name	2-[4-[1-(4-methylsulfonylphenyl)piperidin-4-yl]piperidin-1-yl]pyrazine
Molecular weight	400.541
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.8
Synonyms	SCHEMBL10276215 1-(4-(methylsulfonyl)phenyl)-1''-(pyrazin-2-yl)-4,4''-bipiperidine BDBM50342683
Inchi Key	AZYQJKQMRSQAAQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H28N4O2S/c1-28(26,27)20-4-2-19(3-5-20)24-12-6-17(7-13-24)18-8-14-25(15-9-18)21-16-22-10-11-23-21/h2-5,10-11,16-18H,6-9,12-15H2,1H3
PubChem CID	25012528
ChEMBL	CHEMBL1771084
IUPHAR	N/A
BindingDB	50342683
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
18612	Glucose-dependent insulinotropic receptor	Q7TQP3	Gpr119	Mus musculus (Mouse)	335
18613	Glucose-dependent insulinotropic receptor	Q8TDV5	GPR119	Homo sapiens (Human)	335

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