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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL17334239
Molecular formula	C19H15F3N4O
IUPAC name	2-[(2,4-difluoroanilino)methyl]-5-(4-fluorophenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	372.351
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.1
Synonyms	2-(((2,4-difluorophenyl)amino)methyl)-5-(4-fluorophenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5h)-one US9676782, 28 BDBM196264
Inchi Key	BASQMCLITMNIHO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H15F3N4O/c20-12-1-4-15(5-2-12)25-7-8-26-18(19(25)27)10-14(24-26)11-23-17-6-3-13(21)9-16(17)22/h1-6,9-10,23H,7-8,11H2
PubChem CID	118575000
ChEMBL	N/A
IUPHAR	N/A
BindingDB	196264
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557854	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
557855	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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