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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL181364
Molecular formula	C25H23Cl2NO2S
IUPAC name	6,7-dichloro-2-propyl-5-[[3-(pyridin-4-ylsulfanylmethyl)phenyl]methoxy]-2,3-dihydroinden-1-one
Molecular weight	472.424
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	6.8
Synonyms	BDBM50162565 SCHEMBL4947456 (+/-)-6,7-dichloro-2,3-dihydro-2-propyl-5-[{3-[(4-pyridinylthio)methyl]phenyl}methoxy]-1h-inden-1-one 6,7-Dichloro-2-propyl-5-[3-(pyridin-4-ylsulfanylmethyl)-benzyloxy]-indan-1-one AKOS022180478 6,7-Dichloro-2-propyl-5-((3-((pyridin-4-ylthio)methyl)benzyl)oxy)-2,3-dihydro-1H-inden-1-one [ Show all ]
Inchi Key	BBGQXRGCVLXCQO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H23Cl2NO2S/c1-2-4-18-12-19-13-21(23(26)24(27)22(19)25(18)29)30-14-16-5-3-6-17(11-16)15-31-20-7-9-28-10-8-20/h3,5-11,13,18H,2,4,12,14-15H2,1H3
PubChem CID	11213605
ChEMBL	CHEMBL181364
IUPHAR	N/A
BindingDB	50162565
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
19476	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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