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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL490492
Molecular formula	C28H29N5O5
IUPAC name	N-(2-phenoxyethyl)-2-(pyridin-2-ylmethylamino)-4-(3,4,5-trimethoxyphenyl)pyrimidine-5-carboxamide
Molecular weight	515.57
Hydrogen bond acceptor	9
Hydrogen bond donor	2
XlogP	3.5
Synonyms	BDBM27989 N-(2-phenoxyethyl)-2-[(pyridin-2-ylmethyl)amino]-4-(3,4,5-trimethoxyphenyl)pyrimidine-5-carboxamide trisubstituted pyrimidine analogue, 6j
Inchi Key	BDDFGRUDUYYFFC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H29N5O5/c1-35-23-15-19(16-24(36-2)26(23)37-3)25-22(27(34)30-13-14-38-21-10-5-4-6-11-21)18-32-28(33-25)31-17-20-9-7-8-12-29-20/h4-12,15-16,18H,13-14,17H2,1-3H3,(H,30,34)(H,31,32,33)
PubChem CID	25218707
ChEMBL	CHEMBL490492
IUPHAR	N/A
BindingDB	27989
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20805	Extracellular calcium-sensing receptor	P41180	CASR	Homo sapiens (Human)	1078

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