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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL86365
Molecular formula	C22H23ClN2O2
IUPAC name	7-chloro-4-[(1-methylpiperidin-2-yl)methoxy]-3-phenyl-1H-quinolin-2-one
Molecular weight	382.888
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	4.2
Synonyms	7-Chloro-4-(1-methyl-piperidin-2-ylmethoxy)-3-phenyl-1H-quinolin-2-one 3-Phenyl-4-(1-methylpiperidine-2-ylmethoxy)-7-chloro-1,2-dihydroquinoline-2-one BDBM50081132
Inchi Key	BDRVCSCUCFENQI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H23ClN2O2/c1-25-12-6-5-9-17(25)14-27-21-18-11-10-16(23)13-19(18)24-22(26)20(21)15-7-3-2-4-8-15/h2-4,7-8,10-11,13,17H,5-6,9,12,14H2,1H3,(H,24,26)
PubChem CID	44322272
ChEMBL	CHEMBL86365
IUPHAR	N/A
BindingDB	50081132
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21193	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327

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