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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ZD-7155
Molecular formula	C26H26N6O
IUPAC name	5,7-diethyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3,4-dihydro-1,6-naphthyridin-2-one
Molecular weight	438.535
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	BDBM50049187 NCGC00025043-01 5,7-diethyl-1-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-3,4-dihydro-1,6-naphthyridin-2-one ZD 7155 GTPL8324 ZINC3784334 5,7-Diethyl-1-[2''-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3,4-dihydro-1H-[1,6]naphthyridin-2-one BRD-K11373525-003-01-3 SCHEMBL7286312 5,7-Diethyl-1-{[2'-(1h-Tetrazol-5-Yl)biphenyl-4-Yl]methyl}-3,4-Dihydro-1,6-Naphthyridin-2(1h)-One CHEMBL159096 AC1NGE69 L007754 5,7-diethyl-1-[2'-(1h-1,2,3,4-tetrazol-5-yl)-bi-phenyl-4-ylmethyl]-1,2,3,4-tetrahydro-1,6-naphthyridin-2-one CHEBI:92194 Tocris-1211 5,7-Diethyl-3,4-dihydro-1-[[2'-(1H-tetrazol-5-yl)-1,1'-biphenyl-4-yl]methyl]-1,6-naphthyridin-2(1H)-one D07GQA ZD7 [ Show all ]
Inchi Key	BFVNEYDCFJNLGN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H26N6O/c1-3-19-15-24-22(23(4-2)27-19)13-14-25(33)32(24)16-17-9-11-18(12-10-17)20-7-5-6-8-21(20)26-28-30-31-29-26/h5-12,15H,3-4,13-14,16H2,1-2H3,(H,28,29,30,31)
PubChem CID	4673492
ChEMBL	CHEMBL159096
IUPHAR	N/A
BindingDB	50049187
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
22682	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764
22683	Type-1 angiotensin II receptor	Q9WV26	AGTR1	Cavia porcellus (Guinea pig)	359

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