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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1081654
Molecular formula	C18H22N4O2
IUPAC name	6-(cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Molecular weight	326.4
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.5
Synonyms	BGHQPXFERWTACA-UHFFFAOYSA-N SCHEMBL3025777 6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide BDBM50313325
Inchi Key	BGHQPXFERWTACA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H22N4O2/c1-12-9-14(23)7-8-15(12)22-18(24)16-10-17(20-11-19-16)21-13-5-3-2-4-6-13/h7-11,13,23H,2-6H2,1H3,(H,22,24)(H,19,20,21)
PubChem CID	25182621
ChEMBL	CHEMBL1081654
IUPHAR	N/A
BindingDB	50313325
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23017	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
23015	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
23016	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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