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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL343578
Molecular formula	C21H25ClN4O4S2
IUPAC name	3-[(4-chloro-3-methyl-1,2-oxazol-5-yl)sulfamoyl]-N-[3-[(dimethylamino)methyl]-2,4,6-trimethylphenyl]thiophene-2-carboxamide
Molecular weight	497.025
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	4.0
Synonyms	2-[[[3-[(Dimethylamino)methyl]-2,4,6-trimethylphenyl]amino]carbonyl]-N-(4-chloro-3-methylisoxazole-5-yl)-3-thiophenesulfonamide SCHEMBL6589022
Inchi Key	BGJGHZXKTIGRTO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C21H25ClN4O4S2/c1-11-9-12(2)18(13(3)15(11)10-26(5)6)23-20(27)19-16(7-8-31-19)32(28,29)25-21-17(22)14(4)24-30-21/h7-9,25H,10H2,1-6H3,(H,23,27)
PubChem CID	10117626
ChEMBL	CHEMBL343578
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23059	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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