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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL41677
Molecular formula	C32H38N2O3
IUPAC name	methyl 1-[3-[[2,2-bis(4-methylphenyl)acetyl]amino]propyl]-4-phenylpiperidine-4-carboxylate
Molecular weight	498.667
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.8
Synonyms	1-[3-(Di-p-tolylacetylamino)propyl]-4-phenylpiperidine-4-carboxylic acid methyl ester 1-[3-(2,2-Di-p-tolyl-acetylamino)-propyl]-4-phenyl-piperidine-4-carboxylic acid methyl ester BDBM50090304
Inchi Key	BGURRFIDCHOENU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H38N2O3/c1-24-10-14-26(15-11-24)29(27-16-12-25(2)13-17-27)30(35)33-20-7-21-34-22-18-32(19-23-34,31(36)37-3)28-8-5-4-6-9-28/h4-6,8-17,29H,7,18-23H2,1-3H3,(H,33,35)
PubChem CID	44288485
ChEMBL	CHEMBL41677
IUPHAR	N/A
BindingDB	50090304
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23440	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
23438	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
23439	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572

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