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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL380054
Molecular formula	C18H19FN4
IUPAC name	2-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridine
Molecular weight	310.376
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.3
Synonyms	A3639/0154442 MolPort-000-241-499 2-[4-(4-fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine BDBM50189837 STK684879 2-{[4-(4-fluorophenyl)piperazino]methyl}imidazo[1,2-a]pyridine F3308-0241 AC1LOW22 SR-01000288123 2-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyridine ZINC4628996 MCULE-6071808291 2-((4-(4-fluorophenyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridine AKOS002219664 SR-01000288123-1 2-{[4-(4-fluorophenyl)piperazin-1-yl]methyl}imidazo[1,2-a]pyridine [ Show all ]
Inchi Key	BIARYCFROFVWEW-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H19FN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)13-16-14-23-8-2-1-3-18(23)20-16/h1-8,14H,9-13H2
PubChem CID	1248739
ChEMBL	CHEMBL380054
IUPHAR	N/A
BindingDB	50189837
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24266	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
24263	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
24261	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
24262	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
24265	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
24264	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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