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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL431248
Molecular formula	C30H30F2N4O3
IUPAC name	1-[(2,6-difluorophenyl)methyl]-5-(3-methoxyphenyl)-6-methyl-3-[[(2S)-1-(pyridin-2-ylmethyl)pyrrolidin-2-yl]methyl]pyrimidine-2,4-dione
Molecular weight	532.592
Hydrogen bond acceptor	7
Hydrogen bond donor	0
XlogP	4.1
Synonyms	BDBM50132720 1-(2,6-Difluorobenzyl)-3-[[(2S)-1-(2-pyridinylmethyl)-2alpha-pyrrolidinyl]methyl]-5-(3-methoxyphenyl)-6-methyluracil 1-(2,6-Difluoro-benzyl)-5-(3-methoxy-phenyl)-6-methyl-3-((S)-1-pyridin-2-ylmethyl-pyrrolidin-2-ylmethyl)-1H-pyrimidine-2,4-dione
Inchi Key	BIBBCWVYCRICCF-QHCPKHFHSA-N
Inchi ID	InChI=1S/C30H30F2N4O3/c1-20-28(21-8-5-11-24(16-21)39-2)29(37)36(30(38)35(20)19-25-26(31)12-6-13-27(25)32)18-23-10-7-15-34(23)17-22-9-3-4-14-33-22/h3-6,8-9,11-14,16,23H,7,10,15,17-19H2,1-2H3/t23-/m0/s1
PubChem CID	44340783
ChEMBL	CHEMBL431248
IUPHAR	N/A
BindingDB	50132720
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
24303	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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