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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3702371
Molecular formula	C22H22N2O3
IUPAC name	9-methoxy-2-(5-methoxy-2-methylphenyl)-7,8-dihydro-4H-[1,4]diazepino[7,1-a]isoquinolin-5-one
Molecular weight	362.429
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM135964 SCHEMBL15488609 US8853203, 18
Inchi Key	BIZATFGCHCLCSE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H22N2O3/c1-14-7-8-15(26-2)11-18(14)19-12-20-16-5-4-6-21(27-3)17(16)9-10-24(20)22(25)13-23-19/h4-8,11-12H,9-10,13H2,1-3H3
PubChem CID	73335132
ChEMBL	CHEMBL3702371
IUPHAR	N/A
BindingDB	135964
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
459427	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
459426	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212

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