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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1MRYRM
Molecular formula	C17H20ClN3O3S2
IUPAC name	N-(2-chloro-5-pyrrolidin-1-ylsulfonylphenyl)-2-(thiophen-2-ylmethylamino)acetamide
Molecular weight	413.935
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	2.2
Synonyms	HMS2752P24 ZINC7158368 749907-24-2 MolPort-004-041-566 SMR000369551 MCULE-6938295222 N-(2-chloro-5-pyrrolidin-1-ylsulfonylphenyl)-2-(thiophen-2-ylmethylamino)acetamide CHEMBL1311574 Z52965817 MLS000761240 AKOS034435854 N-[2-chloro-5-(pyrrolidine-1-sulfonyl)phenyl]-2-{[(thiophen-2-yl)methyl]amino}acetamide [ Show all ]
Inchi Key	BJEMMLPLLZDTLH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20ClN3O3S2/c18-15-6-5-14(26(23,24)21-7-1-2-8-21)10-16(15)20-17(22)12-19-11-13-4-3-9-25-13/h3-6,9-10,19H,1-2,7-8,11-12H2,(H,20,22)
PubChem CID	3575923
ChEMBL	CHEMBL1311574
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25003	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
466003	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
25004	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400

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