Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Teflutixol
Molecular formula	C23H26F4N2OS
IUPAC name	2-[4-[3-[6-fluoro-2-(trifluoromethyl)-9H-thioxanthen-9-yl]propyl]piperazin-1-yl]ethanol
Molecular weight	454.528
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	4.6
Synonyms	4-(3-(6-Fluoro-2-(trifluoromethyl)thioxanthen-9-yl)propyl)-1-piperazineethanol CAS_68751 SCHEMBL1041408 EINECS 259-850-8 Teflutixolum AKOS003588975 PDSP1_001121 Tefluxitol 53542-42-0 (di-hydrochloride) CHEMBL2107125 AC1L2ADD Lu-10-022 Teflutixolum [INN-Latin] 2-[4-[3-[6-fluoro-2-(trifluoromethyl)-9H-thioxanthen-9-yl]propyl]piperazin-1-yl]ethanol BDBM81485 PDSP2_001105 55837-23-5 CIS TEFLUTIXOL Teflutixol [INN] AC1Q4K4C NSC_68751 teflutixol[inn] [ Show all ]
Inchi Key	BJWAPFORUPUXRJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H26F4N2OS/c24-17-4-5-19-18(2-1-7-28-8-10-29(11-9-28)12-13-30)20-14-16(23(25,26)27)3-6-21(20)31-22(19)15-17/h3-6,14-15,18,30H,1-2,7-13H2
PubChem CID	68751
ChEMBL	N/A
IUPHAR	N/A
BindingDB	81485
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25512	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
25513	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
25514	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
555576	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218