Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

Ligand

NameLISURIDE
Molecular formulaC20H26N4O
IUPAC name3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea
Molecular weight338.455
Hydrogen bond acceptor2
Hydrogen bond donor2
XlogP2.7
SynonymsLysuride
Lisurida
Lisuridum
18016-80-3
Lisuridum [INN-Latin]
[ Show all ]
Inchi KeyBKRGVLQUQGGVSM-KBXCAEBGSA-N
Inchi IDInChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1
PubChem CID28864
ChEMBLCHEMBL157138
IUPHAR43
BindingDB50056445
DrugBankDB00589

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Total entries: 30
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
260245-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
260395-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
260225-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
260455-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
260215-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
260355-hydroxytryptamine receptor 1DP79400HTR1DSus scrofa (Pig)291
260285-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
260295-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
260435-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
260335-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
5533875-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
5481745-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
5533895-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
442690Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
553388Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
26042Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
26047Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
26032Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
26025Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
26036Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218