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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL374218
Molecular formula	C27H28N2O4
IUPAC name	2-[2-[4-[1-(furan-2-ylmethyl)indol-3-yl]piperidin-1-yl]ethoxy]benzoic acid
Molecular weight	444.531
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.2
Synonyms	SCHEMBL5344015 2-(2-(4-(1-(furan-2-ylmethyl)-1H-indol-3-yl)piperidin-1-yl)ethoxy)benzoic acid BDBM50156865
Inchi Key	BLFHOBLUEABFEX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N2O4/c30-27(31)23-8-2-4-10-26(23)33-17-15-28-13-11-20(12-14-28)24-19-29(18-21-6-5-16-32-21)25-9-3-1-7-22(24)25/h1-10,16,19-20H,11-15,17-18H2,(H,30,31)
PubChem CID	10138404
ChEMBL	CHEMBL374218
IUPHAR	N/A
BindingDB	50156865
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26487	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
26488	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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