Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

Ligand

Namecorynanthine
Molecular formulaC21H26N2O3
IUPAC namemethyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Molecular weight354.45
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP2.9
SynonymsRauhimbine
483-10-3
UNII-F5Z7C9RK8U
F5Z7C9RK8U
Corynanthin
[ Show all ]
Inchi KeyBLGXFZZNTVWLAY-DKJBZYCGSA-N
Inchi IDInChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19-/m0/s1
PubChem CID92766
ChEMBLCHEMBL31410
IUPHARN/A
BindingDB50027058
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
26563Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
26566Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
26570Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
26564Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
26567Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
26568Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
26565Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
26569Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218