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Ligand

NameYohimbine
Molecular formulaC21H26N2O3
IUPAC namemethyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
Molecular weight354.45
Hydrogen bond acceptor4
Hydrogen bond donor2
XlogP2.9
SynonymsYohimbin
Quebrachin
Quebrachine
146-48-5
Corynine
[ Show all ]
Inchi KeyBLGXFZZNTVWLAY-SCYLSFHTSA-N
Inchi IDInChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1
PubChem CID8969
ChEMBLCHEMBL15245
IUPHAR102
BindingDB50013515, 50203564
DrugBankDB01392

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 57
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
265855-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
265965-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
265795-hydroxytryptamine receptor 1BP28222HTR1BHomo sapiens (Human)390
265935-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
265955-hydroxytryptamine receptor 1BP28334Htr1bMus musculus (Mouse)386
266185-hydroxytryptamine receptor 1BO08892HTR1BCavia porcellus (Guinea pig)389
265755-hydroxytryptamine receptor 1DP28221HTR1DHomo sapiens (Human)377
266005-hydroxytryptamine receptor 1DP28565Htr1dRattus norvegicus (Rat)374
266065-hydroxytryptamine receptor 1DP11614HTR1DCanis lupus familiaris (Dog)377
265835-hydroxytryptamine receptor 1EP28566HTR1EHomo sapiens (Human)365
265765-hydroxytryptamine receptor 1FP30940Htr1fRattus norvegicus (Rat)366
266095-hydroxytryptamine receptor 1FP30939HTR1FHomo sapiens (Human)366
266265-hydroxytryptamine receptor 1FQ02284Htr1fMus musculus (Mouse)366
265745-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
266025-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
265725-hydroxytryptamine receptor 2BP30994Htr2bRattus norvegicus (Rat)479
265845-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
265805-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
265915-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
266055-hydroxytryptamine receptor 2CP34968Htr2cMus musculus (Mouse)459

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