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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL434159
Molecular formula	C27H28N6OS
IUPAC name	3-[[4-(4-aminobutyl)-5-quinolin-2-yl-1,2,4-triazol-3-yl]sulfanyl]-1-(7-methyl-1H-indol-3-yl)propan-1-one
Molecular weight	484.622
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	3.7
Synonyms	3-[4-(4-Amino-butyl)-5-quinolin-2-yl-4H-[1,2,4]triazol-3-ylsulfanyl]-1-(7-methyl-1H-indol-3-yl)-propan-1-one BDBM50169465
Inchi Key	BLKXHWDWRVLQGN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H28N6OS/c1-18-7-6-9-20-21(17-29-25(18)20)24(34)13-16-35-27-32-31-26(33(27)15-5-4-14-28)23-12-11-19-8-2-3-10-22(19)30-23/h2-3,6-12,17,29H,4-5,13-16,28H2,1H3
PubChem CID	11705763
ChEMBL	CHEMBL434159
IUPHAR	N/A
BindingDB	50169465
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26746	Somatostatin receptor type 1	P30872	SSTR1	Homo sapiens (Human)	391
26747	Somatostatin receptor type 2	P30874	SSTR2	Homo sapiens (Human)	369
26750	Somatostatin receptor type 3	P32745	SSTR3	Homo sapiens (Human)	418
26748	Somatostatin receptor type 4	P31391	SSTR4	Homo sapiens (Human)	388
26749	Somatostatin receptor type 5	P35346	SSTR5	Homo sapiens (Human)	364

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