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Ligand

NameLorpiprazole
Molecular formulaC21H26F3N5
IUPAC name(1S,8R)-5-[2-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]ethyl]-3,4,6-triazatricyclo[6.3.0.02,6]undeca-2,4-diene
Molecular weight405.469
Hydrogen bond acceptor7
Hydrogen bond donor0
XlogP3.3
Synonyms108785-69-9
SCHEMBL15539135
DB09195
UNII-0M14O7T47Q component BNRMWKUVWLKDQJ-YJBOKZPZSA-N
Inchi KeyBNRMWKUVWLKDQJ-YJBOKZPZSA-N
Inchi IDInChI=1S/C21H26F3N5/c22-21(23,24)16-4-2-5-17(13-16)28-11-9-27(10-12-28)8-7-19-25-26-20-18-6-1-3-15(18)14-29(19)20/h2,4-5,13,15,18H,1,3,6-12,14H2/t15-,18-/m0/s1
PubChem CID20055414
ChEMBLN/A
IUPHARN/A
BindingDBN/A
DrugBankDB09195

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5481945-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5481975-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
548196Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
548195Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
548198Histamine H1 receptorP35367HRH1Homo sapiens (Human)487

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