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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
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Ligand

Name	xylazine
Molecular formula	C12H16N2S
IUPAC name	N-(2,6-dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine
Molecular weight	220.334
Hydrogen bond acceptor	2
Hydrogen bond donor	1
XlogP	2.8
Synonyms	7361-61-7 Rompun N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine Xylazin Narcoxyl Xylzin Xylazinum [INN-Latin] Bayer 1470 Xilazina [INN-Spanish] UNII-2KFG9TP5V8 4H-1,3-Thiazin-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro- BAY 1470 Anased WH 7286 Xylazine (free base) 2-(2,6-Dimethylanilino)-5,6-dihydro-4H-1,3-thiazine EINECS 230-902-1 5,6-Dihydro-2-(2,6-xylidino)-4H-1,3-thiazine 2KFG9TP5V8 2,6-Xylidine, N-(5,6-dihydro-4H-1,3-thiazinyl)- 4H-1,3-Thiazine, 5,6-dihydro-2-(2,6-xylidino)- MLS000054617 CHEMBL297362 2-(2,6-Dimethylphenylamino)-4H-5,6-dihydro-1,3-thiazine BAY-VA-1470 BPICBUSOMSTKRF-UHFFFAOYSA-N NCGC00016098-07 SMR000061135 CAS-7361-61-7 DSSTox_CID_20643 DSSTox_RID_79519 DSSTox_GSID_40643 Primazine Rometar Sedomin Xilazina Xylaxine Xylazinum 4H-1,3-Thiazine-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro- (5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-dimethyl-phenyl)-amine 2-[2,6-Dimethylphenylamino]-4H-5,6-dihydroxthiazine (5,6-Dihydro-4H-[1,3]thiazin-2-yl)-(2,6-dimethyl-phenyl)-amine;N-(2,6-Dimethylphenyl)-5,6-dihydro-4H-1,3-thiazin-2-amine SR-01000075296 Xylazine [USP:INN:BAN] Xylazine [USAN:INN:BAN] Xylapan Xylasol Xylazine(Rompun) xylazine free base Chanazine (TN) Prestwick_962 Rompun (Salt/Mix) 2-(2,6-Dimethylphenylamino)-5,6-dihydro-4H-thiazine hydrochloride Xylapan (Salt/Mix) Xylasol (Salt/Mix) Spectrum_001267 Xylazine (USP/INN) Xylazine, >=99% AC1L1KYH Opera_ID_1260 Prestwick0_000598 Prestwick1_000598 Prestwick2_000598 Prestwick3_000598 Spectrum2_001448 Spectrum3_001472 Spectrum4_000239 Spectrum5_001250 Lopac-X-1251 D0Y2JI Lopac0_001249 SCHEMBL15487 BSPBio_000476 BSPBio_003023 GTPL523 KBioGR_000937 KBioSS_001747 KSC638G6L MLS000881122 DivK1c_000449 SPECTRUM1501200 SPBio_001315 SPBio_002695 BPBio1_000524 ZINC2248 DTXSID3040643 BCBcMAP01_000167 CHEBI:92386 CTK5D8365 HMS501G11 KBio1_000449 KBio2_001747 KBio2_004315 KBio2_006883 KBio3_002523 MolPort-000-869-370 NINDS_000449 HMS1569H18 HMS1921P17 HMS2089E20 HMS2092L07 HMS2096H18 HMS2232F24 HMS3369L20 HMS3713H18 Pharmakon1600-01501200 BCP03045 HY-B0443 KS-00000H9L Tox21_110303 BDBM50027069 BDBM50225286 CCG-39193 KM1558 MFCD00057908 NSC758142 SBB038475 23076-35-9 (mono-hydrochloride) AKOS000115960 Tox21_110303_1 CS-2549 NSC-758142 TRA0042707 IDI1_000449 SMP1_000319 NCGC00016098-01 NCGC00016098-02 NCGC00016098-03 NCGC00016098-04 NCGC00016098-05 NCGC00016098-06 NCGC00016098-08 NCGC00016098-09 NCGC00016098-11 NCGC00038586-02 NCGC00038586-03 NCGC00038586-04 NCGC00038586-05 AC-22589 AJ-08151 AK117805 AS-54468 BC252840 SC-47279 BCP0726000235 SBI-0051216.P003 AB2000618 LS-150494 FT-0654963 X5891 D08683 AB00052246-13 AB00052246-15 AB00052246-16 AB00052246_17 AB00052246_18 361X617 C-46044 L001033 I06-1056 SR-01000075296-4 SR-01000075296-6 BRD-K21565985-001-05-0 BRD-K21565985-001-15-9 (2,6-Dimethyl-phenyl)-[1,3]thiazinan-2-ylidene-amine (2,6-dimethylphenyl)-4,5-dihydro-6H-1,3-thiazin-2-ylamine 4H-1,3-Thiazin-2-amine,N-(2,6-dimethylphenyl)-5,6-dihydro- 4H-1,3-Thiazine-2-amine, N-(2,6-dimethylphenyl)-5,6-dihydro- (9CI) 29335-81-7 [ Show all ]
Inchi Key	BPICBUSOMSTKRF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H16N2S/c1-9-5-3-6-10(2)11(9)14-12-13-7-4-8-15-12/h3,5-6H,4,7-8H2,1-2H3,(H,13,14)
PubChem CID	5707
ChEMBL	CHEMBL297362
IUPHAR	523
BindingDB	50027069
DrugBank	DB11477
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29579	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
29582	Alpha-2A adrenergic receptor	P18871	ADRA2A	Sus scrofa (Pig)	450
29585	Alpha-2A adrenergic receptor	Q01338	Adra2a	Mus musculus (Mouse)	450
29583	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
29580	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
29581	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
29584	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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