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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Histaprodifen
Molecular formula	C20H23N3
IUPAC name	2-[2-(3,3-diphenylpropyl)-1H-imidazol-5-yl]ethanamine
Molecular weight	305.425
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	3.5
Synonyms	2-[2-(3,3-diphenylpropyl)-1h-imidazol-4-yl]ethanamine GTPL4026 ZINC38881558 CHEMBL275507 2-[2-[3,3-di(phenyl)propyl]-3H-imidazol-4-yl]ethanamine BDBM22864 2-[2-(3,3-diphenylpropyl)-1H-imidazol-4-yl]ethan-1-amine D0RG8O SCHEMBL3019488 [ Show all ]
Inchi Key	BPZGZNLONLANFE-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H23N3/c21-14-13-18-15-22-20(23-18)12-11-19(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,15,19H,11-14,21H2,(H,22,23)
PubChem CID	10447834
ChEMBL	CHEMBL275507
IUPHAR	4026
BindingDB	22864
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
30034	5-hydroxytryptamine receptor 1B	P28222	HTR1B	Homo sapiens (Human)	390
30031	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
30035	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
30038	Alpha-1D adrenergic receptor	P23944	Adra1d	Rattus norvegicus (Rat)	561
30030	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
30033	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
30037	Histamine H1 receptor	P31390	Hrh1	Rattus norvegicus (Rat)	486
30032	Histamine H2 receptor	P47747	HRH2	Cavia porcellus (Guinea pig)	359
30040	Histamine H3 receptor	Q9JI35	HRH3	Cavia porcellus (Guinea pig)	445
30039	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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