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Ligand

NameLP-211
Molecular formulaC30H34N4O
IUPAC nameN-[(4-cyanophenyl)methyl]-6-[4-(2-phenylphenyl)piperazin-1-yl]hexanamide
Molecular weight466.629
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP5.0
Synonyms1052147-86-0
AKOS016340412
BDBM50253281
CHEMBL522691
compound 25 [PMID 18800769]
[ Show all ]
Inchi KeyBQEDZLDNNBDKDS-UHFFFAOYSA-N
Inchi IDInChI=1S/C30H34N4O/c31-23-25-14-16-26(17-15-25)24-32-30(35)13-5-2-8-18-33-19-21-34(22-20-33)29-12-7-6-11-28(29)27-9-3-1-4-10-27/h1,3-4,6-7,9-12,14-17H,2,5,8,13,18-22,24H2,(H,32,35)
PubChem CID25107716
ChEMBLCHEMBL522691
IUPHAR8436
BindingDB50253281
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 7
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
302205-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
5367495-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
302165-hydroxytryptamine receptor 7P50407HTR7Cavia porcellus (Guinea pig)446
302185-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
302195-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
5367485-hydroxytryptamine receptor 7P32304Htr7Mus musculus (Mouse)448
30217D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443

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