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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	7beta, 25-dihydroxycholesterol
Molecular formula	C27H46O3
IUPAC name	(3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol
Molecular weight	418.662
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	5.7
Synonyms	BDBM50045543 (3.beta.,7.beta.)-7,25-Dihydroxycholest-5-en-3-ol GTPL4355 7beta,25-dihydroxycholesterol CHEMBL3311219 (3S,7R,8S,9S,10R,13R,14S,17R)-17-[(1R)-5-hydroxy-1,5-dimethyl-hexyl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol SCHEMBL2485860 7.beta.,25-Dihydroxycholesterol AC1LAQHU D0L7PI (3S,7R,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,7-diol [ Show all ]
Inchi Key	BQMSKLCEWBSPPY-CGSQRZAOSA-N
Inchi ID	InChI=1S/C27H46O3/c1-17(7-6-12-25(2,3)30)20-8-9-21-24-22(11-14-27(20,21)5)26(4)13-10-19(28)15-18(26)16-23(24)29/h16-17,19-24,28-30H,6-15H2,1-5H3/t17-,19+,20-,21+,22+,23+,24+,26+,27-/m1/s1
PubChem CID	473142
ChEMBL	N/A
IUPHAR	4355
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553408	G-protein coupled receptor 183	P32249	GPR183	Homo sapiens (Human)	361

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