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Ligand

NameUR-PG55B
Molecular formulaC22H23F2N5O
IUPAC name3,3-bis(4-fluorophenyl)-N-[N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl]propanamide
Molecular weight411.457
Hydrogen bond acceptor5
Hydrogen bond donor3
XlogP3.4
SynonymsBDBM50413176
D0UG1U
3,3-bis(4-fluorophenyl)-N-{N'-[3-(1H-imidazol-5-yl)propyl]carbamimidoyl}propanamide
GTPL1202
CHEMBL513883
Inchi KeyBRPONMOKDIJLJF-UHFFFAOYSA-N
Inchi IDInChI=1S/C22H23F2N5O/c23-17-7-3-15(4-8-17)20(16-5-9-18(24)10-6-16)12-21(30)29-22(25)27-11-1-2-19-13-26-14-28-19/h3-10,13-14,20H,1-2,11-12H2,(H,26,28)(H3,25,27,29,30)
PubChem CID25150704
ChEMBLCHEMBL513883
IUPHAR1202
BindingDB50413176
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
31227Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
31228Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488
31226Histamine H2 receptorP47747HRH2Cavia porcellus (Guinea pig)359

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