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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	oxycodone
Molecular formula	C18H21NO4
IUPAC name	(4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
Molecular weight	315.369
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.2
Synonyms	Thecodine Eucodal ZINC403533 Morphinan-6-one, 4,5-alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- NSC-19043 (-)-Oxycodone Oxicone 4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Oxycodone 0.1 mg/ml in Methanol AC1Q4DTG Oxycodonum C08018 Oxyneo Codeinone,8-dihydro-14-hydroxy- Percodan (TN) DEA No. 9143 Roxiprin (TN) DTXSID5023407 Tylox (TN) Eutagen Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- (8CI) Ossicodone [DCIT] (5alpha)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one Oxycodeinon 4aH-8,5-bcd]furan-5(6H)-one, 7,7a,8,9-tetrahydro-7a-hydroxy-3-methoxy-12-methyl- Oxycodone Hcl Apo-oxycodone CR Oxycone Pancodone Retard D05312 PF06 Dihydrohydroxycondeinone Supendol [Canada] Endocet (TN) Eubine Xtampza Hydroxycodeinon Morphinan-6-one,5.alpha.-epoxy-14-hydroxy-3-methoxy-17-methyl- Oxicodona [INN-Spanish] 14-hydroxy-3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one 76-42-6 Oxycodone [USAN:INN:BAN] BRN 0043446 Oxyfast Codeinone, dihydro-14-hydroxy- Percocet (TN) Roxicet (TN) Dinarkon Tekodin Thekodin Eucodalum Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5alpha)- NSC19043 (1S,5R,13R,17S)-17-hydroxy-10-methoxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0;{1,13}.0;{5,17}.0;{7,18}]octadeca-7(18),8,10-trien-14-one Oxiconum 4,5.alpha.-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Oxycodone 1.0 mg/ml in Methanol AKOS015962233 Oxycodonum [INN-Latin] CD35PMG570 Oxynorm Combunox (TN) Percolone Dihydro-14-hydroxycodeinone SCHEMBL2737 EINECS 200-960-2 Endodan (TN) UNII-CD35PMG570 GTPL7093 Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl-(8CI) Oxanest 124-90-3 Oxycodeinone Oxycodone hydrochloride Avridi Oxycontin CHEMBL656 Pancodone retard (United Kingdom) D0J0TD PTI-821 Dihydrone Supeudol Eubine [France] Xtampza ER LS-92148 NSC 19043 (-)-14-Hydroxydihydrocodeinone Oxicon 14-Hydroxydihydrocodeinone Oxycodone (USAN/INN) AC-16043 Oxycodone/ naloxone controlled release BRUQQQPBMZOVGD-XFKAJCMBSA-N OxyIR Codeinone, dihydrohydroxy- Percodan DB00497 Roxicodone Diphydrone Tekodin (free base) Theocodin Eukodal Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- Ossicodone (4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-one Oxikon 4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one Oxycodone Concentrate AN-22961 Oxycon CHEBI:7852 Pancodine D03SKD PF-00345439 Dihydrohydroxycodeinone Supendol Endine (Australia) Endone WLN: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1 HSDB 3142 Morphinan-6-one,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5.alpha.)- Oxicodona 124-90-3 (hydrochloride) Oxycodon 6-deoxy-7,8-dihydro-14-hydroxy-3-O-methyl-6-oxomorphine Oxycodone solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material BDBM50370595 Oxycontin (TN) Codeinone, 7,8-dihydro-14-hydroxy- Percobarb D0P6KE Remoxy Dihydroxycodeinone Tecodin [ Show all ]
Inchi Key	BRUQQQPBMZOVGD-XFKAJCMBSA-N
Inchi ID	InChI=1S/C18H21NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,13,16,21H,5-9H2,1-2H3/t13-,16+,17+,18-/m1/s1
PubChem CID	5284603
ChEMBL	CHEMBL656
IUPHAR	N/A
BindingDB	50370595
DrugBank	DB00497
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
31364	Delta-type opioid receptor	P41143	OPRD1	Homo sapiens (Human)	372
31367	Delta-type opioid receptor	P33533	Oprd1	Rattus norvegicus (Rat)	372
31361	Kappa-type opioid receptor	P41144	OPRK1	Cavia porcellus (Guinea pig)	380
31365	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
31366	Kappa-type opioid receptor	P33534	Oprk1	Mus musculus (Mouse)	380
31368	Kappa-type opioid receptor	P34975	Oprk1	Rattus norvegicus (Rat)	380
31360	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
31362	Mu-type opioid receptor	P33535	Oprm1	Rattus norvegicus (Rat)	398
31363	Mu-type opioid receptor	P42866	Oprm1	Mus musculus (Mouse)	398

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