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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL223744
Molecular formula	C22H31NO4
IUPAC name	4-[2-[(2S)-2-[(3S)-5-cyclobutyl-3-hydroxypentyl]-5-oxopyrrolidin-1-yl]ethyl]benzoic acid
Molecular weight	373.493
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.8
Synonyms	4-(2-((S)-2-((S)-5-cyclobutyl-3-hydroxypentyl)-5-oxopyrrolidin-1-yl)ethyl)benzoic acid BDBM50156546
Inchi Key	BTPQFLLVGLESRX-PMACEKPBSA-N
Inchi ID	InChI=1S/C22H31NO4/c24-20(11-6-16-2-1-3-16)12-9-19-10-13-21(25)23(19)15-14-17-4-7-18(8-5-17)22(26)27/h4-5,7-8,16,19-20,24H,1-3,6,9-15H2,(H,26,27)/t19-,20-/m0/s1
PubChem CID	11337782
ChEMBL	CHEMBL223744
IUPHAR	N/A
BindingDB	50156546
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
32543	Prostaglandin E2 receptor EP2 subtype	P43116	PTGER2	Homo sapiens (Human)	358
32542	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390
32541	Prostaglandin E2 receptor EP4 subtype	P35408	PTGER4	Homo sapiens (Human)	488

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