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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL474948
Molecular formula	C24H16ClF3N2O4S
IUPAC name	(E)-3-[4-(4-chlorophenoxy)-1-methylindol-3-yl]-N-(2,4,5-trifluorophenyl)sulfonylprop-2-enamide
Molecular weight	520.907
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.3
Synonyms	BDBM50248330 3-(4-(4-chlorophenoxy)-1-methyl-1H-indol-3-yl)-N-(2,4,5-trifluorophenylsulfonyl)acrylamide
Inchi Key	BULYMIPCYGNRBI-BJMVGYQFSA-N
Inchi ID	InChI=1S/C24H16ClF3N2O4S/c1-30-13-14(24-20(30)3-2-4-21(24)34-16-8-6-15(25)7-9-16)5-10-23(31)29-35(32,33)22-12-18(27)17(26)11-19(22)28/h2-13H,1H3,(H,29,31)/b10-5+
PubChem CID	44564934
ChEMBL	CHEMBL474948
IUPHAR	N/A
BindingDB	50248330
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33168	Prostaglandin E2 receptor EP3 subtype	P43115	PTGER3	Homo sapiens (Human)	390

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