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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL225441
Molecular formula	C27H37N3O3
IUPAC name	5-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(8-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)pentanamide
Molecular weight	451.611
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.0
Synonyms	BDBM50157782 N-(8-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-4-(2-methoxyphenyl)-1-piperazinepentanamide
Inchi Key	BUMLEIQSRWKWTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H37N3O3/c1-32-24-13-4-3-12-23(24)30-19-17-29(18-20-30)16-6-5-15-26(31)28-22-11-7-9-21-10-8-14-25(33-2)27(21)22/h3-4,8,10,12-14,22H,5-7,9,11,15-20H2,1-2H3,(H,28,31)
PubChem CID	11432453
ChEMBL	CHEMBL225441
IUPHAR	N/A
BindingDB	50157782
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33178	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
33177	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448

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