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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL389842
Molecular formula	C19H23N5O3
IUPAC name	7-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-1,3-dimethyl-9H-purine-2,6,8-trione
Molecular weight	369.425
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	0.6
Synonyms	BDBM50213574 7-{3-[1,2,3,4-tetrahydroisoquinolin-2-yl]-propyl}-1,3-dimethyl-7,9-dihydro-3H-purine-2,6,8-trione
Inchi Key	BUYJPECXLSATLM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H23N5O3/c1-21-16-15(17(25)22(2)19(21)27)24(18(26)20-16)10-5-9-23-11-8-13-6-3-4-7-14(13)12-23/h3-4,6-7H,5,8-12H2,1-2H3,(H,20,26)
PubChem CID	44424671
ChEMBL	CHEMBL389842
IUPHAR	N/A
BindingDB	50213574
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33449	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
33451	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
33450	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448

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