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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL144799
Molecular formula	C22H27ClN4O3
IUPAC name	ethyl 4-(butylamino)-1-(2-chloro-3-phenoxypropyl)pyrazolo[3,4-b]pyridine-5-carboxylate
Molecular weight	430.933
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	5.1
Synonyms	BDBM50120448 4-Butylamino-1-(2-chloro-3-phenoxy-propyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester
Inchi Key	BVNPWCKOPYUPOU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H27ClN4O3/c1-3-5-11-24-20-18-13-26-27(21(18)25-12-19(20)22(28)29-4-2)14-16(23)15-30-17-9-7-6-8-10-17/h6-10,12-13,16H,3-5,11,14-15H2,1-2H3,(H,24,25)
PubChem CID	10862925
ChEMBL	CHEMBL144799
IUPHAR	N/A
BindingDB	50120448
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
33898	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
33899	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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