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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL144710
Molecular formula	C25H31FN4O
IUPAC name	3-[2-[4-[3-(4-fluorophenyl)-5-methylindol-1-yl]piperidin-1-yl]ethyl]-1,1-dimethylurea
Molecular weight	422.548
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	3.9
Synonyms	1-[2-[4-[3-(4-Fluorophenyl)-5-methyl-1H-indol-1-yl]-1-piperidinyl]ethyl]-3,3-dimethylurea BDBM50001817 SCHEMBL9273642 3-(2-{4-[3-(4-Fluoro-phenyl)-5-methyl-indol-1-yl]-piperidin-1-yl}-ethyl)-1,1-dimethyl-urea
Inchi Key	BYYHVUKATBOAAS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31FN4O/c1-18-4-9-24-22(16-18)23(19-5-7-20(26)8-6-19)17-30(24)21-10-13-29(14-11-21)15-12-27-25(31)28(2)3/h4-9,16-17,21H,10-15H2,1-3H3,(H,27,31)
PubChem CID	10093723
ChEMBL	CHEMBL144710
IUPHAR	N/A
BindingDB	50001817
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
36203	Alpha-1A adrenergic receptor	P43140	Adra1a	Rattus norvegicus (Rat)	466
36202	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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