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Ligand

NameCR6086
Molecular formulaC26H27F3N2O3
IUPAC name4-[1-[[(7R)-6-[[4-(trifluoromethyl)phenyl]methyl]-6-azaspiro[2.5]octane-7-carbonyl]amino]cyclopropyl]benzoic acid
Molecular weight472.508
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP2.6
Synonyms4-{1-[(5R)-6-{[4-(trifluoromethyl)phenyl]methyl}-6-azaspiro[2.5]octane-5-amido]cyclopropyl}benzoic acid
GTPL9845
UNII-SS2LQQ8094 component CADWTPLFEZSAHM-OAQYLSRUSA-N
Inchi KeyCADWTPLFEZSAHM-OAQYLSRUSA-N
Inchi IDInChI=1S/C26H27F3N2O3/c27-26(28,29)20-5-1-17(2-6-20)16-31-14-13-24(9-10-24)15-21(31)22(32)30-25(11-12-25)19-7-3-18(4-8-19)23(33)34/h1-8,21H,9-16H2,(H,30,32)(H,33,34)/t21-/m1/s1
PubChem CID133081958
ChEMBLN/A
IUPHAR9845
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
553432Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513
553433Prostaglandin E2 receptor EP4 subtypeP43114Ptger4Rattus norvegicus (Rat)488
553434Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488

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